Hydrochlorothiazide (Microzide, HydroDiuril)

Classification

Thiazide Diuretic

Mechanism of Action

Indications

Hypertension, edema

Dosage and Administration

12.5-25 mg once daily

Forms

Tablet, capsule

Side Effects

Hypokalemia, dizziness, headache

Contraindications

Anuria, hypersensitivity to sulfonamide-derived drugs

Interactions

Increased risk of electrolyte imbalances with corticosteroids

Precautions

Monitor electrolytes, particularly potassium, regularly

Pharmacokinetics

Absorbed orally, excreted unchanged in urine

Pharmacodynamics

Reduces blood pressure by decreasing blood volume

Storage Requirements

Store at room temperature, protect from light

Patient Counselling

Take in the morning to avoid nocturia