Levothyroxine - Drug Details

Classification

Thyroid Hormone Replacement

Mechanism of Action

Indications

Hypothyroidism

Dosage and Administration

25-200 mcg once daily, depending on the patient�s thyroid levels

Forms

Tablet, capsule, injection

Side Effects

Palpitations, weight loss, insomnia

Contraindications

Untreated thyrotoxicosis, acute myocardial infarction

Interactions

May alter the effects of antidiabetic drugs, anticoagulants

Precautions

Monitor thyroid function tests regularly

Pharmacokinetics

Absorbed in the intestines, metabolized to T3 in the liver and other tissues, excreted in urine

Pharmacodynamics

Replaces or supplements thyroid hormone

Storage Requirements

Store at room temperature, protect from light

Levothyroxine (Synthroid, Levoxyl)