Warfarin - Drug Details

Classification

Anticoagulant, Vitamin K Antagonist

Mechanism of Action

Indications

Prevention of thromboembolic disorders

Dosage and Administration

Dose adjusted based on INR, usually 2-10 mg once daily

Forms

Tablet

Side Effects

Bleeding, bruising, gastrointestinal upset

Contraindications

Pregnancy, active bleeding, uncontrolled hypertension

Interactions

Increased bleeding risk with NSAIDs, antibiotics, and certain foods rich in vitamin K

Precautions

Monitor INR regularly and adjust dose accordingly

Pharmacokinetics

Absorbed orally, metabolized in the liver, excreted in urine

Pharmacodynamics

Prevents blood clots by reducing clotting factor production

Storage Requirements

Store at room temperature, away from light and moisture

Warfarin (Coumadin)