Levothyroxine (Synthroid, Levoxyl)

Classification

Thyroid hormone

Mechanism of Action

Indications

Hypothyroidism

Dosage and Administration

25-200 mcg orally once daily

Forms

Tablets, injection

Side Effects

Palpitations, weight loss, heat intolerance

Contraindications

Untreated thyrotoxicosis, acute myocardial infarction

Interactions

May increase the effects of anticoagulants

Precautions

Monitor thyroid function tests regularly

Pharmacokinetics

Half-life: 7 days, primarily metabolized in the liver

Pharmacodynamics

Increases metabolic rate and affects protein synthesis

Storage Requirements

Store at room temperature, protect from light

Patient Counselling

Take on an empty stomach, 30 minutes before breakfast